LGG-13. SYNERGISTIC TREATMENT FOR PEDIATRIC LOW GRADE GLIOMA WITH THE DUAL MTORC1/2 INHIBITOR TAK-228 AND MEK INHIBITOR TRAMETINIB

Pediatric low-grade glioma (PLGG) is one of the most common childhood tumors. If the tumor is located in a brain region that is not accessible for surgical resection, additional therapies are needed. Recent studies highlighted the important role of mTORC and MEK-activation in PLGG. The dual mTORC1/2...

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Vydáno v:Neuro Oncol
Hlavní autoři: Arnold, Antje, Rodriguez, Fausto, Eberhart, Charles, Raabe, Eric
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2017
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5475204/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nox083.146
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