TMOD-10. INTRACRANIAL PATIENT-DERIVED XENOGRAFT FROM A PEDIATRIC GLIOBLASTOMA RETAINS MOLECULAR CHARACTERISTICS AND GROWTH PATHWAYS

BACKGROUND: Pediatric glioblastomas (pGBM) are characterized by overlapping and unique molecular driver mutations compared to their adult counterparts. Primary cell cultures and patient-derived xenograft (PDX) models of pGBM are rare which may contribute to difficulty in advancing patient outcomes....

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Vydáno v:Neuro Oncol
Hlavní autoři: White, Angela R., Kumar, Shiva Senthil, Smith, Amanda R., Ramkissoon, Annmarie, Oatman, Nicole, Dasgupta, Biplab, Breese, Erin H., Stevenson, Charles, Fuller, Christine, Fouladi, Maryam, DeWire, Mariko D., Drissi, Rachid, Chow, Lionel M.L.
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2017
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5475184/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nox083.209
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