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TMOD-10. INTRACRANIAL PATIENT-DERIVED XENOGRAFT FROM A PEDIATRIC GLIOBLASTOMA RETAINS MOLECULAR CHARACTERISTICS AND GROWTH PATHWAYS

BACKGROUND: Pediatric glioblastomas (pGBM) are characterized by overlapping and unique molecular driver mutations compared to their adult counterparts. Primary cell cultures and patient-derived xenograft (PDX) models of pGBM are rare which may contribute to difficulty in advancing patient outcomes....

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Publicado en:Neuro Oncol
Main Authors: White, Angela R., Kumar, Shiva Senthil, Smith, Amanda R., Ramkissoon, Annmarie, Oatman, Nicole, Dasgupta, Biplab, Breese, Erin H., Stevenson, Charles, Fuller, Christine, Fouladi, Maryam, DeWire, Mariko D., Drissi, Rachid, Chow, Lionel M.L.
Formato: Artigo
Idioma:Inglês
Publicado: Oxford University Press 2017
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5475184/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nox083.209
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