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MEDU-29. A NOVEL MOUSE MODEL OF PI3 KINASE PATHWAY IN METASTATIC SHH MEDULLOBLASTOMA
Sleeping Beauty transposon mutagenesis in Shh medulloblastomas enabled us to identify that Pten was a common insertion site in both primary tumor and matched spinal metastases, suggesting PI3 kinase pathway is important for the progression of Shh medulloblastoma, in particular, for its metastasis. A...
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| Publicado no: | Neuro Oncol |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5475146/ https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nox083.179 |
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