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IMMU-19. IMMUNE RESPONSE OF MOUSE HEDGEHOG MEDULLOBLASTOMA TREATED WITH SMOOTHENED INHIBITOR
Sonic hedgehog subgroup medullloblastoma is driven by activation of the hedgehog pathway. This discovery presented the first opportunity for a treatment based on molecular-targeted therapy. Inhibition of the pathway by a small molecule, Smoothened inhibitor, arrests tumor cell proliferation and incr...
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| Pubblicato in: | Neuro Oncol |
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| Autori principali: | , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Oxford University Press
2017
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5475110/ https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nox083.129 |
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