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IMMU-19. IMMUNE RESPONSE OF MOUSE HEDGEHOG MEDULLOBLASTOMA TREATED WITH SMOOTHENED INHIBITOR

Sonic hedgehog subgroup medullloblastoma is driven by activation of the hedgehog pathway. This discovery presented the first opportunity for a treatment based on molecular-targeted therapy. Inhibition of the pathway by a small molecule, Smoothened inhibitor, arrests tumor cell proliferation and incr...

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Detalhes bibliográficos
Publicado no:Neuro Oncol
Main Authors: Dang, Mai, Jain, Kanika, Van Dang, Chi, Curran, Tom, Haldar, Malay
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5475110/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nox083.129
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