IMMU-17. TRANSGENIC EXPRESSION OF IL15 IMPROVES ANTIGLIOMA ACTIVITY OF IL13RΑ2-CAR T CELLS

The goal of this project is to develop T-cells expressing IL13Rα2-specific chimeric antigen receptor (CAR) as an effective immunotherapy for diffuse intrinsic pontine glioma (DIPG) and glioblastoma (GBM), the most aggressive, highly lethal, primary human brain tumors in children. We recently demonst...

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Publicat a:Neuro Oncol
Autors principals: Steffin, David, Prinzing, Brooke, Yi, Zhongzhen, Balyasnikova, Irina, Dotti, Gianpietro, Gottschalk, Stephen, Krenciute, Giedre
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2017
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5475109/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nox083.127
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