EPND-13. YAP1-MAMLD1 FUSIONS ALONE ARE SUFFICIENT TO FORM SUPRATENTORIAL EPENDYMOMA-LIKE TUMORS IN MICE

Oncogenic fusions containing RELA or YAP1 have recently been identified as genetic hallmarks of distinct molecular subgroups of supratentorial ependymomas (ST-EPN), designated as ST-EPN-RELA and ST-EPN-YAP1, respectively. The lack of adequate models for ST-EPN-YAP1 has so far hindered the developmen...

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Publicat a:Neuro Oncol
Autors principals: Pajtler, Kristian W., Brabetz, Sebastian, Capper, David, Vouri, Mikaella, Mauermann, Monika, Mack, Norman, Sieber, Laura, Witt, Hendrik, Jones, David T. W., Korshunov, Andrey, Pfister, Stefan M., Kool, Marcel, Kawauchi, Daisuke
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2017
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Abstracts
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5475096/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nox083.071
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