HGG-11. THE Β-CATENIN/CBP-ANTAGONIST ICG-001 INHIBITS PEDIATRIC GLIOMA GROWTH IN A WNT-INDEPENDENT MANNER

Pediatric high-grade gliomas (pedHGG) belong to the most aggressive cancers in children with a poor prognosis due to a lack of efficient therapeutic strategies. The β-catenin/Wnt-signaling pathway was shown to hold promising potential as a treatment target in adult high-grade gliomas by abrogating t...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Neuro Oncol
Main Authors: Wiese, Maria, Walther, Neele, Diederichs, Christopher, Schill, Fabian, Monecke, Sebastian, Salinas, Gabriela, Sturm, Dominik, Dressel, Ralf, Pfister, Stefan M., Kramm, Christof M.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2017
Assuntos:
Abstracts
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5475074/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nox083.100
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados