Laddar...

Canonical Wnt pathway inhibitor ICG-001 induces cytotoxicity of multiple myeloma cells in Wnt-independent manner.

Canonical Wnt signaling has been implicated in the regulation of multiple myeloma (MM) growth. Here, we investigated whether the targeting of this pathway with a novel pharmacological inhibitor ICG-001 would result in an anti-tumor effect and improvement of chemosensitivity in MM. As expected, ICG-0...

Full beskrivning

Sparad:
Bibliografiska uppgifter
Huvudupphovsmän: Eileen R Grigson, Maria Ozerova, Alexandra Pisklakova, Hao Liu, Daniel M Sullivan, Yulia Nefedova
Materialtyp: Artigo
Språk:Inglês
Publicerad: Public Library of Science (PLoS) 2015-01-01
Serie:PLoS ONE
Länkar:http://europepmc.org/articles/PMC4311909?pdf=render
Taggar: Lägg till en tagg
Inga taggar, Lägg till första taggen!