The β-catenin/CBP-antagonist ICG-001 inhibits pediatric glioma tumorigenicity in a Wnt-independent manner

Pediatric high-grade gliomas (pedHGG) belong to the most aggressive cancers in children with a poor prognosis due to a lack of efficient therapeutic strategies. The β-catenin/Wnt-signaling pathway was shown to hold promising potential as a treatment target in adult high-grade gliomas by abrogating t...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Wiese, Maria, Walther, Neele, Diederichs, Christopher, Schill, Fabian, Monecke, Sebastian, Salinas, Gabriela, Sturm, Dominik, Pfister, Stefan M., Dressel, Ralf, Johnsen, Steven A., Kramm, Christof M.
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2017
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5432336/
https://ncbi.nlm.nih.gov/pubmed/28460484
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.15934
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