DIPG-33. BIOLOGICAL CHARACTERIZATION OF PPM1D MUTATIONS IN THE CONTEXT OF DIPG

Recent genomic analyses of pediatric gliomas have implicated truncating mutations within Protein Phosphatase, Mg2+/Mn2+ dependent 1D (PPM1D) as one of a handful of driving events responsible for the formation and proliferation of diffuse intrinsic pontine gliomas (DIPGs). Also an identified oncogene...

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Publicado en:Neuro Oncol
Autores principales: Fons, Nathan, Sundaram, Ranjini, Surovtseva, Yulia, Rusin, Scott, Kettenbach, Arminja, Breuer, Gregory, Bindra, Ranjit
Formato: Artigo
Lenguaje:Inglês
Publicado: Oxford University Press 2017
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5475004/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nox083.048
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