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DIPG-24. EPIGENETIC ANALYSIS OF FORMALIN-FIXED PARAFFIN-EMBEDDED PEDIATRIC GLIOMA TISSUE
BACKGROUND: Diffuse midline gliomas are uniquely characterized by missense mutations in Histone H3 isoforms H3.3 and H3.1, associated with distinct gene, protein and methylation profiles and poorer clinical outcomes. As a result, mutant H3 protein is of great interest as a potential driver of pediat...
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| Publicado no: | Neuro Oncol |
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| Main Authors: | , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5474999/ https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nox083.039 |
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