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ATRT-01. OVEREXPRESSION OF TEAD4 IN ATYPICAL TERATOID/RHABDOID TUMOR: NEW INSIGHT TO THE PATHOPHYSIOLOGY OF AN AGGRESSIVE BRAIN TUMOR

BACKGROUND: Atypical teratoid/rhabdoid tumor (AT/RT) is a highly malignant embryonal brain tumor that occurs mainly in early childhood. Although most of the tumors are characterized by inactivating mutations of the tumor suppressor gene, SMARCB1, the biological basis of its tumorigenesis and aggress...

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Detalhes bibliográficos
Publicado no:Neuro Oncol
Main Authors: Suzuki, Mario, Kondo, Akihide, Ogino, Ikuko, Arai, Hajime, Tomita, Tadanori, Sredni, Simone T.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5474969/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nox083.000
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