ATRT-01. OVEREXPRESSION OF TEAD4 IN ATYPICAL TERATOID/RHABDOID TUMOR: NEW INSIGHT TO THE PATHOPHYSIOLOGY OF AN AGGRESSIVE BRAIN TUMOR

BACKGROUND: Atypical teratoid/rhabdoid tumor (AT/RT) is a highly malignant embryonal brain tumor that occurs mainly in early childhood. Although most of the tumors are characterized by inactivating mutations of the tumor suppressor gene, SMARCB1, the biological basis of its tumorigenesis and aggress...

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Publicado en:Neuro Oncol
Main Authors: Suzuki, Mario, Kondo, Akihide, Ogino, Ikuko, Arai, Hajime, Tomita, Tadanori, Sredni, Simone T.
Formato: Artigo
Idioma:Inglês
Publicado: Oxford University Press 2017
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5474969/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nox083.000
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