Bam-dependent deubiquitinase complex can disrupt germ-line stem cell maintenance by targeting cyclin A

Drosophila germ-line stem cells (GSCs) provide an excellent model to study the regulatory mechanisms of stem cells in vivo. Bag of marbles (bam) has been demonstrated to be necessary and sufficient to promote GSC and cystoblast differentiation. Despite extensive investigation of its regulation and g...

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Pubblicato in:Proc Natl Acad Sci U S A
Autori principali: Ji, Shanming, Li, Chaoyi, Hu, Lin, Liu, Kehui, Mei, Jie, Luo, Yuewan, Tao, Yi, Xia, Zongping, Sun, Qinmiao, Chen, Dahua
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2017
Soggetti:
Biological Sciences
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5474830/
https://ncbi.nlm.nih.gov/pubmed/28484036
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1619188114
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