Bam-dependent deubiquitinase complex can disrupt germ-line stem cell maintenance by targeting cyclin A

Drosophila germ-line stem cells (GSCs) provide an excellent model to study the regulatory mechanisms of stem cells in vivo. Bag of marbles (bam) has been demonstrated to be necessary and sufficient to promote GSC and cystoblast differentiation. Despite extensive investigation of its regulation and g...

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Publicat a:Proc Natl Acad Sci U S A
Autors principals: Ji, Shanming, Li, Chaoyi, Hu, Lin, Liu, Kehui, Mei, Jie, Luo, Yuewan, Tao, Yi, Xia, Zongping, Sun, Qinmiao, Chen, Dahua
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2017
Matèries:
Biological Sciences
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5474830/
https://ncbi.nlm.nih.gov/pubmed/28484036
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1619188114
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