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Direct Inhibition of Pumilo Activity by Bam and Bgcn in Drosophila Germ Line Stem Cell Differentiation

The fate of stem cells is intricately regulated by numerous extrinsic and intrinsic factors that promote maintenance or differentiation. The RNA-binding translational repressor Pumilio (Pum) in conjunction with Nanos (Nos) is required for self-renewal, whereas Bam (bag-of-marbles) and Bgcn (benign g...

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Detalhes bibliográficos
Main Authors: Kim, Ji Young, Lee, Young Chul, Kim, Changsoo
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2836079/
https://ncbi.nlm.nih.gov/pubmed/20018853
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.002014
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