Bam-dependent deubiquitinase complex can disrupt germ-line stem cell maintenance by targeting cyclin A

Drosophila germ-line stem cells (GSCs) provide an excellent model to study the regulatory mechanisms of stem cells in vivo. Bag of marbles (bam) has been demonstrated to be necessary and sufficient to promote GSC and cystoblast differentiation. Despite extensive investigation of its regulation and g...

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Bibliografiske detaljer
Udgivet i:Proc Natl Acad Sci U S A
Main Authors: Ji, Shanming, Li, Chaoyi, Hu, Lin, Liu, Kehui, Mei, Jie, Luo, Yuewan, Tao, Yi, Xia, Zongping, Sun, Qinmiao, Chen, Dahua
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2017
Fag:
Biological Sciences
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5474830/
https://ncbi.nlm.nih.gov/pubmed/28484036
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1619188114
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