Bam-dependent deubiquitinase complex can disrupt germ-line stem cell maintenance by targeting cyclin A

Drosophila germ-line stem cells (GSCs) provide an excellent model to study the regulatory mechanisms of stem cells in vivo. Bag of marbles (bam) has been demonstrated to be necessary and sufficient to promote GSC and cystoblast differentiation. Despite extensive investigation of its regulation and g...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Ji, Shanming, Li, Chaoyi, Hu, Lin, Liu, Kehui, Mei, Jie, Luo, Yuewan, Tao, Yi, Xia, Zongping, Sun, Qinmiao, Chen, Dahua
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2017
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5474830/
https://ncbi.nlm.nih.gov/pubmed/28484036
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1619188114
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