Worldwide differences in the incidence of type I diabetes are associated with amino acid variation at position 57 of the HLA-DQ beta chain.

Ítems similars

• Aspartic acid at position 57 of the HLA-DQ beta chain protects against type I diabetes: a family study.
  per: Morel, P A, et al.
  Publicat: (1988)
• HLA-DR antigens and HLA-DQ beta chain polymorphism in susceptibility to rheumatoid arthritis.
  per: Ilonen, J, et al.
  Publicat: (1990)
• Critical contribution of beta chain residue 57 in peptide binding ability of both HLA-DR and -DQ molecules.
  per: Nepom, B S, et al.
  Publicat: (1996)
• A combination of HLA-DQ beta Asp57-negative and HLA DQ alpha Arg52 confers susceptibility to insulin-dependent diabetes mellitus.
  per: Khalil, I, et al.
  Publicat: (1990)
• Polymorphic DQ alpha and DQ beta interactions dictate HLA class II determinants of allo-recognition
  Publicat: (1990)