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Critical contribution of beta chain residue 57 in peptide binding ability of both HLA-DR and -DQ molecules.

Position 57 in the beta chain of HLA class II molecules maintains an Asp/non-Asp dimorphism that has been conserved through evolution and is implicated in susceptibility to some autoimmune diseases. The latter effect may be due to the influence of this residue on the ability of class II alleles to b...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Principais autores: Nepom, B S, Nepom, G T, Coleman, M, Kwok, W W
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 1996
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC38960/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8692969/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.93.14.7202
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