Critical contribution of beta chain residue 57 in peptide binding ability of both HLA-DR and -DQ molecules.
Position 57 in the beta chain of HLA class II molecules maintains an Asp/non-Asp dimorphism that has been conserved through evolution and is implicated in susceptibility to some autoimmune diseases. The latter effect may be due to the influence of this residue on the ability of class II alleles to b...
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| Publicado no: | Proc Natl Acad Sci U S A |
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| Principais autores: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
1996
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC38960/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8692969/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.93.14.7202 |
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