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Th17 Polarization under Hypoxia Results in Increased IL-10 Production in a Pathogen-Independent Manner
The IL-17-producing CD4(+) T helper cell (Th17) differentiation is affected by stimulation of the aryl hydrocarbon receptor (AhR) pathway and by hypoxia-inducible factor 1 alpha (HIF-1α). In some cases, Th17 become non-pathogenic and produce IL-10. However, the initiating events triggering this phen...
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| Udgivet i: | Front Immunol |
|---|---|
| Main Authors: | , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Frontiers Media S.A.
2017
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5474482/ https://ncbi.nlm.nih.gov/pubmed/28674533 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2017.00698 |
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