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Potential Application of Klotho in Human Chronic Kidney Disease
The extracellular domain of transmembrane alpha-Klotho (αKlotho, hereinafter simply called Klotho) is cleaved by secretases and released into the circulation as soluble Klotho. Soluble Klotho in the circulation starts to decline early in chronic kidney disease (CKD) stage 2 and urinary Klotho possib...
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| 發表在: | Bone |
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| Main Authors: | , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
2017
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5474175/ https://ncbi.nlm.nih.gov/pubmed/28115282 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bone.2017.01.017 |
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