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Potential Application of Klotho in Human Chronic Kidney Disease

The extracellular domain of transmembrane alpha-Klotho (αKlotho, hereinafter simply called Klotho) is cleaved by secretases and released into the circulation as soluble Klotho. Soluble Klotho in the circulation starts to decline early in chronic kidney disease (CKD) stage 2 and urinary Klotho possib...

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Dades bibliogràfiques
Publicat a:Bone
Autors principals: Neyra, Javier A., Hu, Ming Chang
Format: Artigo
Idioma:Inglês
Publicat: 2017
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5474175/
https://ncbi.nlm.nih.gov/pubmed/28115282
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bone.2017.01.017
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