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Non-invasive measurement of mTORC1 signaling with (89)Zr-transferrin
PURPOSE: mTOR regulates many normal physiological processes and when hyperactive, can drive numerous cancers and human diseases. However, it is very challenging to detect and quantify mTOR signaling non-invasively in clinically relevant animal models of disease or man. We hypothesized that a nuclear...
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| Gepubliceerd in: | Clin Cancer Res |
|---|---|
| Hoofdauteurs: | , , , , , , , |
| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
2016
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5474159/ https://ncbi.nlm.nih.gov/pubmed/28007777 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-16-2448 |
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