RIAM (Rap1-interacting adaptor molecule) regulates complement-dependent phagocytosis

Phagocytosis mediated by the complement receptor CR3 (also known as integrin α(M)ß(2) or Mac-1) is regulated by the recruitment of talin to the cytoplasmic tail of the ß(2) integrin subunit. Talin recruitment to this integrin is dependent on Rap1 activation. However, the mechanism by which Rap1 regu...

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Detalhes bibliográficos
Publicado no:Cell Mol Life Sci
Main Authors: Medraño-Fernandez, Iria, Reyes, Raquel, Olazabal, Isabel, Rodriguez, Elena, Sanchez-Madrid, Francisco, Boussiotis, Vassiliki A., Reche, Pedro A., Cabañas, Carlos, Lafuente, Esther M.
Formato: Artigo
Idioma:Inglês
Publicado em: SP Birkhäuser Verlag Basel 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5474120/
https://ncbi.nlm.nih.gov/pubmed/23420480
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00018-013-1268-6
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