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Preparation of pure populations of covalently stabilized amyloid β-protein oligomers of specific sizes

Evidence suggests that amyloid β-protein (Aβ) oligomers may be seminal pathogenic agents in Alzheimer's disease (AD). If so, developing oligomer-targeted therapeutics requires an understanding of oligomer structure. This has been difficult due to the instability of these non-covalently associat...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Anal Biochem
Prif Awduron: Hayden, Eric Y., Conovaloff, Joseph L., Mason, Ashley, Bitan, Gal, Teplow, David B.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2016
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5474095/
https://ncbi.nlm.nih.gov/pubmed/27810329
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ab.2016.10.026
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