Structural Characterization of the SMRT Corepressor Interacting with Histone Deacetylase 7

The 2525 amino acid SMRT corepressor is an intrinsically disordered hub protein responsible for binding and coordinating the activities of multiple transcription factors and chromatin modifying enzymes. Here we have studied its interaction with HDAC7, a class IIa deacetylase that interacts with the...

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Udgivet i:Sci Rep
Main Authors: Desravines, Danielle C., Serna Martin, Itziar, Schneider, Robert, Mas, Philippe J., Aleksandrova, Nataliia, Jensen, Malene Ringkjøbing, Blackledge, Martin, Hart, Darren J.
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2017
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5473869/
https://ncbi.nlm.nih.gov/pubmed/28623264
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-03718-5
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