Structural Characterization of the SMRT Corepressor Interacting with Histone Deacetylase 7

The 2525 amino acid SMRT corepressor is an intrinsically disordered hub protein responsible for binding and coordinating the activities of multiple transcription factors and chromatin modifying enzymes. Here we have studied its interaction with HDAC7, a class IIa deacetylase that interacts with the...

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Bibliografske podrobnosti
izdano v:Sci Rep
Main Authors: Desravines, Danielle C., Serna Martin, Itziar, Schneider, Robert, Mas, Philippe J., Aleksandrova, Nataliia, Jensen, Malene Ringkjøbing, Blackledge, Martin, Hart, Darren J.
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group UK 2017
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5473869/
https://ncbi.nlm.nih.gov/pubmed/28623264
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-03718-5
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