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Activation of p53 Transcriptional Activity by SMRT: a Histone Deacetylase 3-Independent Function of a Transcriptional Corepressor

The silencing mediator of retinoic acid and thyroid hormone receptors (SMRT) is an established histone deacetylase 3 (HDAC3)-dependent transcriptional corepressor. Microarray analyses of MCF-7 cells transfected with control or SMRT small interfering RNA revealed SMRT regulation of genes involved in...

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Bibliographic Details
Main Authors: Adikesavan, Anbu Karani, Karmakar, Sudipan, Pardo, Patricia, Wang, Liguo, Liu, Shuang, Li, Wei, Smith, Carolyn L.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2014
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3993559/
https://ncbi.nlm.nih.gov/pubmed/24449765
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.01216-13
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