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Mutations in the Pneumocystis jirovecii DHPS Gene Confer Cross-Resistance to Sulfa Drugs
Pneumocystis jirovecii is a major opportunistic pathogen that causes Pneumocystis pneumonia (PCP) and results in a high degree of mortality in immunocompromised individuals. The drug of choice for PCP is typically sulfamethoxazole (SMX) or dapsone in conjunction with trimethoprim. Drug treatment fai...
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
American Society for Microbiology
2005
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| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC547354/ https://ncbi.nlm.nih.gov/pubmed/15673759 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.49.2.741-748.2005 |
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