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Immune deficiency due to high copy numbers of an Ak beta transgene.

Because allelic polymorphism of the major histocompatibility complex class II antigens affects the immune response at several levels, we wished to characterize the contribution of a particular alpha or beta chain in vivo using transgenic mice. We have established and characterized 12 lines of H-2s/s...

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Autores principales: Gilfillan, S, Aiso, S, Michie, S A, McDevitt, H O
Formato: Artigo
Lenguaje:Inglês
Publicado: 1990
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC54735/
https://ncbi.nlm.nih.gov/pubmed/2119506
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