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Immune deficiency due to high copy numbers of an Ak beta transgene.

Because allelic polymorphism of the major histocompatibility complex class II antigens affects the immune response at several levels, we wished to characterize the contribution of a particular alpha or beta chain in vivo using transgenic mice. We have established and characterized 12 lines of H-2s/s...

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Udgivet i:Proc Natl Acad Sci U S A
Principais autores: Gilfillan, S, Aiso, S, Michie, S A, McDevitt, H O
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 1990
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC54735/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2119506/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.87.18.7319
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