Evolution of major histocompatibility complex class II allelic diversity: direct descent in mice and humans.

The high degree of polymorphism seen at major histocompatibility complex (MHC) class II loci is a feature unique to the MHC. Most of the beta-chain polymorphism is localized in "hypervariable" regions (HVRs). HVR amino acid sequence similarity between distantly related species has recently been foun...

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Veröffentlicht in:	Proc Natl Acad Sci U S A
Hauptverfasser:	Lundberg, A S, McDevitt, H O
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	National Academy of Sciences 1992
Schlagworte:	Research Article
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC49538/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1631156/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.89.14.6545
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