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Allelic diversity is generated by intraexon sequence exchange at the DRB1 locus of primates.

The loci encoding the class II cell surface antigens HLA-DR, -DQ, and -DP exhibit a remarkable degree of allelic polymorphism. Most of the class II allelic diversity is localized to the second exon, which encodes a beta-pleated sheet followed by an alpha-helical domain. Here, phylogenetic analysis o...

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Detalhes bibliográficos
Main Authors: Gyllensten, U B, Sundvall, M, Erlich, H A
Formato: Artigo
Idioma:Inglês
Publicado em: 1991
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC51517/
https://ncbi.nlm.nih.gov/pubmed/2023919
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