Allelic diversity is generated by intraexon sequence exchange at the DRB1 locus of primates.
The loci encoding the class II cell surface antigens HLA-DR, -DQ, and -DP exhibit a remarkable degree of allelic polymorphism. Most of the class II allelic diversity is localized to the second exon, which encodes a beta-pleated sheet followed by an alpha-helical domain. Here, phylogenetic analysis o...
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| Publicado no: | Proc Natl Acad Sci U S A |
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| Principais autores: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
1991
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC51517/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2023919/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.88.9.3686 |
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