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Interspecies Recombination in Type II Topoisomerase Genes Is Not a Major Cause of Fluoroquinolone Resistance in Invasive Streptococcus pneumoniae Isolates in the United States

Mutations in the topoisomerase type II enzymes account for fluoroquinolone resistance in Streptococcus pneumoniae. These mutations can arise spontaneously or be transferred by intraspecies or interspecies recombination, primarily with viridans streptococci. We analyzed the nucleotide sequences of th...

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Bibliografische gegevens
Hoofdauteurs: Pletz, Mathias W. R., McGee, Lesley, Beall, Bernard, Whitney, Cynthia G., Klugman, Keith P.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society for Microbiology 2005
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC547348/
https://ncbi.nlm.nih.gov/pubmed/15673766
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.49.2.779-780.2005
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