Interspecies Recombination in Type II Topoisomerase Genes Is Not a Major Cause of Fluoroquinolone Resistance in Invasive Streptococcus pneumoniae Isolates in the United States

Mutations in the topoisomerase type II enzymes account for fluoroquinolone resistance in Streptococcus pneumoniae. These mutations can arise spontaneously or be transferred by intraspecies or interspecies recombination, primarily with viridans streptococci. We analyzed the nucleotide sequences of th...

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Detalhes bibliográficos
Main Authors: Pletz, Mathias W. R., McGee, Lesley, Beall, Bernard, Whitney, Cynthia G., Klugman, Keith P.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2005
Assuntos:
Mechanisms of Resistance
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC547348/
https://ncbi.nlm.nih.gov/pubmed/15673766
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.49.2.779-780.2005
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