Prevalence of First-Step Mutants among Levofloxacin-Susceptible Invasive Isolates of Streptococcus pneumoniae in the United States

By use of a PCR-restriction fragment length polymorphism assay, we screened 496 levofloxacin-susceptible invasive pneumococcal strains (MIC ≤ 2 mg/liter) for quinolone resistance-determining region mutations known to confer fluoroquinolone resistance. Among those with a levofloxacin MIC of 2 mg/lite...

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Bibliografiske detaljer
Main Authors: Pletz, Mathias W. R., Shergill, Ardaman P., McGee, Lesley, Beall, Bernard, Whitney, Cynthia G., Klugman, Keith P.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2006
Fag:
Mechanisms of Resistance
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1426940/
https://ncbi.nlm.nih.gov/pubmed/16569885
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.50.4.1561-1563.2006
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