JUN IS A KEY TRANSCRIPTIONAL REGULATOR OF THE UNFOLDED PROTEIN RESPONSE IN ACUTE MYELOID LEUKEMIA

The transcription factor JUN is frequently overexpressed in multiple genetic sub-types of acute myeloid leukemia (AML), however, the functional role of JUN in AML is not well defined. Here we report that shRNA-mediated inhibition of JUN decreases AML cell survival and propagation in vivo. By perform...

Descripció completa

Guardat en:
Dades bibliogràfiques
Publicat a:Leukemia
Autors principals: Zhou, Chun, Martinez, Esteban, Di Marcantonio, Daniela, Solanki-Patel, Nehal, Aghayev, Turan, Peri, Suraj, Ferraro, Francesca, Skorski, Tomasz, Scholl, Claudia, Fröhling, Stefan, Balachandran, Siddharth, Wiest, David L., Sykes, Stephen M.
Format: Artigo
Idioma:Inglês
Publicat: 2016
Matèries:
Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5473421/
https://ncbi.nlm.nih.gov/pubmed/27840425
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/leu.2016.329
Etiquetes: Afegir etiqueta
Sense etiquetes, Sigues el primer a etiquetar aquest registre!

Ítems similars