Combination Therapy with Amphotericin B Lipid Complex and Caspofungin Acetate of Disseminated Zygomycosis in Diabetic Ketoacidotic Mice

We studied the combination of amphotericin B lipid complex (ABLC) and caspofungin in mice with disseminated Rhizopus oryzae. Combination therapy improved survival compared to that of mice given monotherapy and that of untreated controls (P < 0.05) but did not improve organ clearance. In addition,...

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Bibliographic Details
Main Authors: Spellberg, Brad, Fu, Yue, Edwards, John E., Ibrahim, Ashraf S.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2005
Subjects:
Experimental Therapeutics
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC547325/
https://ncbi.nlm.nih.gov/pubmed/15673781
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.49.2.830-832.2005
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