Posaconazole Mono- or Combination Therapy for Treatment of Murine Zygomycosis

We compared the efficacy of combination posaconazole-liposomal amphotericin B (LAmB) therapy to monotherapy with either drug in diabetic ketoacidotic or neutropenic mice with disseminated zygomycosis caused by Rhizopus oryzae. Combination therapy was no better than LAmB alone, and posaconazole monot...

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Bibliografiske detaljer
Main Authors: Ibrahim, Ashraf S., Gebremariam, Teclegiorgis, Schwartz, Julie A., Edwards, John E., Spellberg, Brad
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology (ASM) 2009
Fag:
Experimental Therapeutics
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2630615/
https://ncbi.nlm.nih.gov/pubmed/18936190
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01124-08
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