Mutation of tlyA Confers Capreomycin Resistance in Mycobacterium tuberculosis

Capreomycin, an important drug for the treatment of multidrug-resistant tuberculosis, is a macrocyclic peptide antibiotic produced by Saccharothrix mutabolis subspecies capreolus. The basis of resistance to this drug was investigated by isolating and characterizing capreomycin-resistant strains of M...

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Detalles Bibliográficos
Autores principales: Maus, Courtney E., Plikaytis, Bonnie B., Shinnick, Thomas M.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology 2005
Materias:
Mechanisms of Resistance
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC547314/
https://ncbi.nlm.nih.gov/pubmed/15673735
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.49.2.571-577.2005
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