Replicable in vivo physiological and behavioral phenotypes of the Shank3B null mutant mouse model of autism

BACKGROUND: Autism spectrum disorder (ASD) is a clinically and biologically heterogeneous condition characterized by social, repetitive, and sensory behavioral abnormalities. No treatments are approved for the core diagnostic symptoms of ASD. To enable the earliest stages of therapeutic discovery an...

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Publicado en:Mol Autism
Autores principales: Dhamne, Sameer C., Silverman, Jill L., Super, Chloe E., Lammers, Stephen H. T., Hameed, Mustafa Q., Modi, Meera E., Copping, Nycole A., Pride, Michael C., Smith, Daniel G., Rotenberg, Alexander, Crawley, Jacqueline N., Sahin, Mustafa
Formato: Artigo
Lenguaje:Inglês
Publicado: BioMed Central 2017
Materias:
Research
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5472997/
https://ncbi.nlm.nih.gov/pubmed/28638591
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13229-017-0142-z
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