Reduced Excitatory Neurotransmission and Mild Autism-Relevant Phenotypes in Adolescent Shank3 Null Mutant Mice

Mutations in the synaptic scaffolding protein gene SHANK3 are strongly implicated in autism and Phelan–McDermid 22q13 deletion syndrome. The precise location of the mutation within the Shank3 gene is key to its phenotypic outcomes. Here, we report the physiological and behavioral consequences of nul...

Celý popis

Uloženo v:
Podrobná bibliografie
Hlavní autoři: Yang, Mu, Bozdagi, Ozlem, Scattoni, Maria Luisa, Wöhr, Markus, Roullet, Florence I., Katz, Adam M., Abrams, Danielle N., Kalikhman, David, Simon, Harrison, Woldeyohannes, Leuk, Zhang, James Y., Harris, Mark J., Saxena, Roheeni, Silverman, Jill L., Buxbaum, Joseph D., Crawley, Jacqueline N.
Médium: Artigo
Jazyk:Inglês
Vydáno: Society for Neuroscience 2012
Témata:
Articles
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3362928/
https://ncbi.nlm.nih.gov/pubmed/22573675
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.6107-11.2012
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky