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Down-Regulation of CD62L Shedding in T Cells by CD39(+) Regulatory T Cells Leads to Defective Sensitization in Contact Hypersensitivity Reactions

Injection of regulatory T cells (Tregs) followed by sensitization with 2,4,6-trinitrochlorobenzene induced a transient increase in size and cellularity of skin-draining lymph nodes (LNs) in mice. This led us to hypothesize that Tregs may affect the trafficking of T cells from and to peripheral LNs....

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Detalhes bibliográficos
Publicado no:J Invest Dermatol
Main Authors: Mahnke, Karsten, Useliene, Jurgina, Ring, Sabine, Kage, Paula, Jendrossek, Verena, Robson, Simon C., Bylaite-Bucinskiene, Matilda, Steinbrink, Kerstin, Enk, Alexander H.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5472987/
https://ncbi.nlm.nih.gov/pubmed/27623510
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jid.2016.08.023
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