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Antibody Targeting of “Steady-State” Dendritic Cells Induces Tolerance Mediated by Regulatory T Cells

Dendritic cells (DCs) are often defined as pivotal inducers of immunity, but these proinflammatory properties only develop after stimulation or ex vivo manipulation of DCs. Under non-inflammatory conditions in vivo, DCs are embedded into a tissue environment and encounter a plethora of self-antigens...

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Detalles Bibliográficos
Publicado en:Front Immunol
Main Authors: Mahnke, Karsten, Ring, Sabine, Enk, Alexander H.
Formato: Artigo
Idioma:Inglês
Publicado: Frontiers Media S.A. 2016
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4763042/
https://ncbi.nlm.nih.gov/pubmed/26941742
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2016.00063
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