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AcrAB Efflux Pump Plays a Role in Decreased Susceptibility to Tigecycline in Morganella morganii
Transposon mutagenesis of a clinical isolate of Morganella morganii, G1492 (tigecycline MIC of 4 μg/ml), yielded two insertion knockout mutants for which tigecycline MICs were 0.03 μg/ml. Transposon insertions mapped to acrA, which is constitutively overexpressed in G1492, suggesting a role of the A...
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| Vydáno v: | Antimicrob Agents Chemother |
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| Hlavní autoři: | , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
American Society for Microbiology (ASM)
2005
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC547285/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15673770/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/AAC.49.2.791-793.2005 |
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