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AcrAB Multidrug Efflux Pump Is Associated with Reduced Levels of Susceptibility to Tigecycline (GAR-936) in Proteus mirabilis

Tigecycline has good broad-spectrum activity against many gram-positive and gram-negative pathogens with the notable exception of the Proteeae. A study was performed to identify the mechanism responsible for the reduced susceptibility to tigecycline in Proteus mirabilis. Two independent transposon i...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Visalli, Melissa A., Murphy, Ellen, Projan, Steven J., Bradford, Patricia A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2003
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC151746/
https://ncbi.nlm.nih.gov/pubmed/12543675
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.47.2.665-669.2003
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