A Molecular Mechanism To Switch the Aryl Hydrocarbon Receptor from a Transcription Factor to an E3 Ubiquitin Ligase

The aryl hydrocarbon receptor (AhR) is a ligand-activated transcription factor that is known as a mediator of toxic responses. Recently, it was shown that the AhR has dual functions. Besides being a transcription factor, it also possesses an intrinsic E3 ubiquitin ligase function that targets, e.g.,...

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Xehetasun bibliografikoak
Argitaratua izan da:Mol Cell Biol
Egile Nagusiak: Luecke-Johansson, Sandra, Gralla, Michael, Rundqvist, Helene, Ho, Jolene Caifeng, Johnson, Randall S., Gradin, Katarina, Poellinger, Lorenz
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society for Microbiology 2017
Gaiak:
Research Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC5472827/
https://ncbi.nlm.nih.gov/pubmed/28416634
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00630-16
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