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Specific ablation of mouse Fam20C in cells expressing type I collagen leads to skeletal defects and hypophosphatemia
FAM20C mutations in humans cause Raine syndrome and our previous studies showed that global inactivation of mouse Fam20C led to bone and dental defects. By crossbreeding 2.3 kb Col 1a1-Cre mice with Fam20C (flox/flox) mice, we created 2.3 kb Col 1a1-Cre;Fam20C (foxl/flox) (cKO) mice, in which Fam2...
Αποθηκεύτηκε σε:
| Τόπος έκδοσης: | Sci Rep |
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| Κύριοι συγγραφείς: | , , , , , , |
| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
Nature Publishing Group UK
2017
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| Θέματα: | |
| Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5472603/ https://ncbi.nlm.nih.gov/pubmed/28620244 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-03960-x |
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