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A systematic approach to determining the identifiability of multistage carcinogenesis models

Multistage clonal expansion (MSCE) models of carcinogenesis are continuous-time Markov process models often used to relate cancer incidence to biological mechanism. Identifiability analysis determines what model parameter combinations can, theoretically, be estimated from given data. We use a system...

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Bibliographic Details
Published in:Risk Anal
Main Authors: Brouwer, Andrew F., Meza, Rafael, Eisenberg, Marisa C.
Format: Artigo
Language:Inglês
Published: 2016
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5472511/
https://ncbi.nlm.nih.gov/pubmed/27612302
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/risa.12684
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