Improved Synthesis of the C-Glucuronide/Glycoside of 4-Hydroxybenzylretinone (4-HBR)

Improvements in the synthesis of carbon-linked glucuronide/glucoside conjugates of cancer chemopreventive retinoids have been achieved starting with 2,3,4,6-tetra-O-benzyl-D-glucopyranose. The revised approach demonstrates better yields, eliminates the use of an expensive, carcinogenic protecting gr...

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Bibliographic Details
Published in:J Carbohydr Chem
Main Authors: Cavanaugh, Kathryn R., Narayanasamy, Sureshbabu, Walker, Joel R., Clagett-Dame, Margaret, Curley, Robert W.
Format: Artigo
Language:Inglês
Published: 2016
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5472352/
https://ncbi.nlm.nih.gov/pubmed/28626297
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/07328303.2016.1227831
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